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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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World-2DPAGE Portal
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q9UM05
USC-OGP 2-DE database
:
Q9UM05
Q9UM05
General information about the entry
View entry in simple text format
Entry name
SC31A_HUMAN
Primary accession number
Q9UM05
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Protein transport protein Sec31A; AltName: Full=ABP125; AltName: Full=ABP130; AltName: Full=SEC31-like protein 1; AltName: Full=SEC31-related protein A; AltName: Full=Web1-like protein;.
Gene name
Name=SEC31A
Synonyms=KIAA0905, SEC31L1
ORFNames=HSPC275, HSPC334
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1094
:
pI=6.11; Mw=155482
Cross-references
UniProtKB/Swiss-Prot
O94979; SC31A_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
SC31A_HUMAN
Primary accession number
O94979
Secondary accession number(s)
B4DIW6 B7ZKZ7 B7ZL00 H7C2W3 Q17RR5 Q5H9P6 Q5XG74 Q659G7 Q6ZU90 Q7LCX9 Q86TJ0 Q8IZH4 Q9P048 Q9P0A6 Q9UM05 Q9UM06
Sequence was last modified on
July 10, 2007 (version 3)
Annotations were last modified on
March 15, 2017 (version 144)
Name and origin of the protein
Description
RecName: Full=Protein transport protein Sec31A; AltName: Full=ABP125; AltName: Full=ABP130; AltName: Full=SEC31-like protein 1; AltName: Full=SEC31-related protein A; AltName: Full=Web1-like protein;
Gene name
Name=SEC31A
Synonyms=KIAA0905, SEC31L1
ORFNames=HSPC275, HSPC334
Encoded on
Name=SEC31A; Synonyms=KIAA0905, SEC31L1; ORFNames=HSPC275, HSPC334
Keywords
3D-structure
;
Alternative splicing
;
Chromosomal rearrangement
;
Complete proteome
;
Cytoplasm
;
Cytoplasmic vesicle
;
Endoplasmic reticulum
;
ER-Golgi transport
;
Isopeptide bond
;
Membrane
;
Phosphoprotein
;
Polymorphism
;
Protein transport
;
Proto-oncogene
;
Reference proteome
;
Repeat
;
Transport
;
Ubl conjugation
;
WD repeat
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AF139184; AAF67836.1
; -; mRNA
EMBL
AB018358; BAA84923.1
; -; mRNA
EMBL
AB018359; BAA84924.1
; -; mRNA
EMBL
AB020712; BAA74928.2
; -; mRNA
EMBL
AK125897; BAC86336.1
; -; mRNA
EMBL
AK295810; BAG58628.1
; -; mRNA
EMBL
AL049463; CAH56418.1
; -; mRNA
EMBL
CR933696; CAI45995.1
; ALT_SEQ; mRNA
EMBL
AC021105; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
AC108469; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
CH471057; EAX05908.1
; -; Genomic_DNA
EMBL
BC047883; AAH47883.1
; -; mRNA
EMBL
BC084583; AAH84583.1
; -; mRNA
EMBL
BC117221; AAI17222.1
; -; mRNA
EMBL
BC143489; AAI43490.1
; -; mRNA
EMBL
BC143491; AAI43492.1
; -; mRNA
EMBL
BC143492; AAI43493.1
; -; mRNA
EMBL
AY137583; AAN15221.1
; -; mRNA
EMBL
AF161393; AAF28953.1
; ALT_FRAME; mRNA
EMBL
AF161452; AAF29012.1
; ALT_FRAME; mRNA
CCDS
CCDS3596.1; -. [O94979-1]
; .
CCDS
CCDS3597.1; -. [O94979-4]
; .
CCDS
CCDS43244.1; -. [O94979-3]
; .
CCDS
CCDS47088.1; -. [O94979-2]
; .
CCDS
CCDS54773.1; -. [O94979-9]
; .
CCDS
CCDS75155.1; -. [O94979-6]
; .
CCDS
CCDS75156.1; -. [O94979-10]
; .
RefSeq
NP_001070674.1; NM_001077206.3. [O94979-3]
; .
RefSeq
NP_001070675.1; NM_001077207.3. [O94979-1]
; .
RefSeq
NP_001070676.1; NM_001077208.3. [O94979-2]
; .
RefSeq
NP_001177978.1; NM_001191049.2. [O94979-9]
; .
RefSeq
NP_001287673.1; NM_001300744.2. [O94979-6]
; .
RefSeq
NP_001287674.1; NM_001300745.2. [O94979-10]
; .
RefSeq
NP_001305048.1; NM_001318119.1. [O94979-2]
; .
RefSeq
NP_001305049.1; NM_001318120.1. [O94979-1]
; .
RefSeq
NP_057295.2; NM_016211.4. [O94979-4]
; .
UniGene
Hs.370024; -
; .
UniGene
Hs.617723; -
; .
UniGene
Hs.728916; -
; .
PDB
3WXA; X-ray
; 2.36 A; C/D=837-848
PDBsum
3WXA; -
; .
ProteinModelPortal
O94979; -
; .
SMR
O94979; -
; .
BioGrid
116539; 51
; .
DIP
DIP-40438N; -
; .
IntAct
O94979; 36
; .
MINT
MINT-3002555; -
; .
STRING
9606.ENSP00000347329; -
; .
TCDB
3.A.5.9.1; the general secretory pathway (sec) family
; .
iPTMnet
O94979; -
; .
PhosphoSitePlus
O94979; -
; .
SwissPalm
O94979; -
; .
BioMuta
SEC31A; -
; .
EPD
O94979; -
; .
MaxQB
O94979; -
; .
PaxDb
O94979; -
; .
PeptideAtlas
O94979; -
; .
PRIDE
O94979; -
; .
Ensembl
ENST00000311785; ENSP00000309070
; ENSG00000138674. [O94979-3]; .
Ensembl
ENST00000348405; ENSP00000337602
; ENSG00000138674. [O94979-4]; .
Ensembl
ENST00000355196; ENSP00000347329
; ENSG00000138674. [O94979-1]; .
Ensembl
ENST00000395310; ENSP00000378721
; ENSG00000138674. [O94979-1]; .
Ensembl
ENST00000443462; ENSP00000408027
; ENSG00000138674. [O94979-9]; .
Ensembl
ENST00000448323; ENSP00000400926
; ENSG00000138674. [O94979-1]; .
Ensembl
ENST00000500777; ENSP00000421464
; ENSG00000138674. [O94979-6]; .
Ensembl
ENST00000505984; ENSP00000424451
; ENSG00000138674. [O94979-10]; .
Ensembl
ENST00000508502; ENSP00000424635
; ENSG00000138674. [O94979-2]; .
Ensembl
ENST00000509142; ENSP00000426569
; ENSG00000138674. [O94979-3]; .
Ensembl
ENST00000513858; ENSP00000426886
; ENSG00000138674. [O94979-6]; .
GeneID
22872; -
; .
KEGG
hsa:22872; -
; .
UCSC
uc003hnf.3; human. [O94979-1]
; .
CTD
22872; -
; .
DisGeNET
22872; -
; .
GeneCards
SEC31A; -
; .
HGNC
HGNC:17052; SEC31A
; .
HPA
HPA005457; -
; .
MIM
610257; gene
; .
neXtProt
NX_O94979; -
; .
OpenTargets
ENSG00000138674; -
; .
PharmGKB
PA162402737; -
; .
eggNOG
KOG0307; Eukaryota
; .
eggNOG
ENOG410XQ1D; LUCA
; .
GeneTree
ENSGT00390000003175; -
; .
HOGENOM
HOG000230582; -
; .
HOVERGEN
HBG055626; -
; .
InParanoid
O94979; -
; .
KO
K14005; -
; .
PhylomeDB
O94979; -
; .
TreeFam
TF313842; -
; .
Reactome
R-HSA-204005; COPII (Coat Protein 2) Mediated Vesicle Transport
; .
Reactome
R-HSA-2132295; MHC class II antigen presentation
; .
Reactome
R-HSA-381038; XBP1(S) activates chaperone genes
; .
Reactome
R-HSA-983170; Antigen Presentation: Folding
; assembly and peptide loading of class I MHC; .
SignaLink
O94979; -
; .
ChiTaRS
SEC31A; human
; .
GeneWiki
SEC31A; -
; .
GenomeRNAi
22872; -
; .
PRO
PR:O94979; -
; .
Proteomes
UP000005640; Chromosome 4
; .
Bgee
ENSG00000138674; -
; .
ExpressionAtlas
O94979; baseline and differential
; .
Genevisible
O94979; HS
; .
GO
GO:0030127; C:COPII vesicle coat
; NAS:UniProtKB; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0005783; C:endoplasmic reticulum
; IDA:UniProtKB; .
GO
GO:0070971; C:endoplasmic reticulum exit site
; IMP:UniProtKB; .
GO
GO:0005789; C:endoplasmic reticulum membrane
; TAS:Reactome; .
GO
GO:0030134; C:ER to Golgi transport vesicle
; IDA:UniProtKB; .
GO
GO:0012507; C:ER to Golgi transport vesicle membrane
; TAS:Reactome; .
GO
GO:0000139; C:Golgi membrane
; IEA:GOC; .
GO
GO:0043231; C:intracellular membrane-bounded organelle
; IDA:HPA; .
GO
GO:0048471; C:perinuclear region of cytoplasm
; IDA:UniProtKB; .
GO
GO:0030120; C:vesicle coat
; IDA:MGI; .
GO
GO:0048306; F:calcium-dependent protein binding
; IPI:UniProtKB; .
GO
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II
; TAS:Reactome; .
GO
GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I
; TAS:Reactome; .
GO
GO:0048208; P:COPII vesicle coating
; TAS:Reactome; .
GO
GO:0006888; P:ER to Golgi vesicle-mediated transport
; NAS:UniProtKB; .
GO
GO:0036498; P:IRE1-mediated unfolded protein response
; TAS:Reactome; .
GO
GO:0015031; P:protein transport
; IEA:UniProtKB-KW; .
GO
GO:0051592; P:response to calcium ion
; IDA:UniProtKB; .
Gene3D
2.130.10.10; -
; 1; .
InterPro
IPR024298; ACE1_Sec16_Sec31
; .
InterPro
IPR015943; WD40/YVTN_repeat-like_dom
; .
InterPro
IPR001680; WD40_repeat
; .
InterPro
IPR017986; WD40_repeat_dom
; .
Pfam
PF12931; Sec16_C
; 1; .
SMART
SM00320; WD40
; 6; .
SUPFAM
SSF50978; SSF50978
; 1; .
PROSITE
PS50082; WD_REPEATS_2
; 1; .
PROSITE
PS50294; WD_REPEATS_REGION
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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